Discussion questions

1. Summarize and clarify the information needs for assessing and managing the development of pest resistance to transgenic products.

2. What methodologies, information, and data address the regulatory needs for assessing and managing the development of pest resistance?

3. What is the state of the science that addresses the regulatory needs for assessing and managing the development of pest resistance?

4. What research needs for assessing and managing the development of pest resistance might be predicted over the next 5 years, based on current agricultural trends and emerging biotechnology products?

5. Are there other topics that are not included that should be a priority for assessing and managing the development of pest resistance?

6. What research gaps exist for assessing and managing the development of pest resistance and how might these best be addressed?

7. What priority rankings (high, medium, low, or not a priority) should be placed on any topic identified as a research gap?

Topics that may be addressed:

1. Risk Assessment
   1. Effect of transgenic plant on:
      1. Pest biology and ecology
      2. Pest population genetics and dynamics
         1. Single vs. multi-gene effects
      3. Pest selection intensity (dose)
      4. Pest predictive models
   2. What are appropriate controls for transgenic comparisons?

2. Risk Management and Monitoring/Remedial Action
   1. Changes in agricultural management practices
      1. Refuges
      2. Purposeful plantings
      3. Crop rotations
      4. GE trait rotation
      5. Prescriptive uses
      6. Gene stacking
   2. Restricted gene expression (tissue specific or temporally restricted expression)